Endothelium is the inner layer of vessels that separates circulating blood from the rest of the
body tissues. Since its discovery, it has been involved in various functions, both systemic and
organ specific. Currently, endothelial damage and failure in its functions is considered a key
element in pathophysiology of various clinical scenarios, among which we may find COVID-19.
Hence, it has been a target in development of strategies that seek to maintain, enhance or
repair its function. The purpose of the following review is to describe what an endothelial
function is about, its relation with current medical practice, and its implications in the SARSCoV-2 pandemic.
Maldonado C, F., Valdés A, C., Díaz P, C., Valls J, N., Romero P, C., Cerda A, Óscar, & Cáceres Ll, M. (2021). Disfunción endotelial. Mecanismos e implicancias en Covid-19. Revista Hospital Clínico Universidad De Chile, 32(3). https://doi.org/10.5354/2735-7996.2021.69442